MicroRNA expression profile in plasma from type 1 diabetic patients: Case-control study and bioinformatic analysis

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چکیده

منابع مشابه

Chaotic dynamic analysis and nonlinear control of blood glucose regulation system in type 1 diabetic patients

In this paper, chaotic dynamic and nonlinear control in a glucose-insulin system in types I diabetic patients and a healthy person have been investigated. Chaotic analysis methods of the blood glucose system include Lyapunov exponent and power spectral density based on the time series derived from the clinical data. Wolf's algorithm is used to calculate the Lyapunov exponent, which positive val...

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MicroRNA expression profiles and type 1 diabetes mellitus: systematic review and bioinformatic analysis

Growing evidence indicates that microRNAs (miRNAs) have a key role in processes involved in type 1 diabetes mellitus (T1DM) pathogenesis, including immune system functions and beta-cell metabolism and death. Although dysregulated miRNA profiles have been identified in T1DM patients, results are inconclusive; with only few miRNAs being consistently dysregulated among studies. Thus, we performed ...

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Quality of Life in Diabetic Patients: A Case-Control Study

Objective: Quality of life (QOL) is an intellectual concept consisting of positive and negative aspects of an individual’s life and indeed it demonstrates the method by which a person perceives the health condition as well as the other aspects of his/her life and reacts to them. Currently, assessment of QOL is more considered because of the increased prevalence of chronic diseases. So, the curr...

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Increased Expression of TRAIL and Its Receptors on Peripheral T-Cells in Type 1 Diabetic Patients

Background: Type-I diabetes is an autoimmune inflammatory disease in which pancreatic ß-cells are selectively destroyed by infiltrating cells. TNF-related apoptosis-inducing ligand (TRAIL) is a type-II membrane protein of the TNF superfamily which is expressed in different tissues, including pancreas and lymphocytes. In humans, TRAIL interacts with four membrane receptors. TRAIL-R1 and TRAIL-R2...

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ژورنال

عنوان ژورنال: Diabetes Research and Clinical Practice

سال: 2018

ISSN: 0168-8227

DOI: 10.1016/j.diabres.2018.03.044